Artists are sorted according to their surnames
| Artist | Number of songs |
|---|---|
| U-style | 1 |
| U.D.O. | 90 |
| U.K. SUBS | 11 |
| U2 | 257 |
| U96 | 5 |
| UNDOit | 1 |
| US 5 | 249 |
| US5 | 58 |
| USA For Africa | 1 |
| UVERworld | 2 |
| Udg | 59 |
| Udo | 8 |
| Uffie | 3 |
| Ugly | 5 |
| Ugly Kid Joe | 1 |
| Ugo | 2 |
| Uhlíř Jaroslav a Svěrák Zdeněk | 72 |
| Uhlíř, Jaroslav | 92 |
| Ulm, Aleš | 1 |
| Ulrychovi, Petr a Hana | 23 |
| Ultimo | 1 |
| Ultraviolet | 4 |
| Ultravox | 42 |
| Unabomber | 1 |
| Uncle Bob | 1 |
| Uncle Cracker | 1 |
| Underoath | 43 |
| Underside | 4 |
| Underwood, Carrie | 52 |
| Underworld | 17 |
| Ungrová, Anna | 12 |
| Unheiling | 1 |
| Uniklubi | 63 |
| Unikový Východ | 12 |
| Unique II | 1 |
| United Flavour | 3 |
| Uniting Nations | 1 |
| Unk | 1 |
| Unsun | 24 |
| Unwritten Law | 69 |
| Upíří skalyna | 1 |
| Urban Cookie Collective | 1 |
| Urban symphony | 1 |
| Urbanize | 1 |
| Urbanová, Míša | 3 |
| Uriah Heep | 264 |
| Used, The | 99 |
| Usher | 154 |
| Utada | 13 |
| Utah Saints | 2 |
| Uzumaki,Naruto | 1 |
| Už jsme doma | 6 |
